Anti-Cyfra21-1 (CK19) McAb (coating)

Name: Anti-Cyfra21-1 (CK19) McAb (coating)
Brand: Hainan Medikament Trading Co., Ltd.

McAb to Cyfra21-1(CK19)

Anti-Cyfra21-1 (CK19) McAb (coating) Specifications

Catalog #: L1C00706

Specificity: Cytokeratin is a subunit of human glandular epithelia. It has 20 different types dividing into two subgroups: class I (acidic protein), class II (basic protein). Cytokeratin is a polymer composed of class I and class II keratin. Cell keratin 19 (CK19) is one of the lowest molecular weight of about 400 KDa. CK19 is widely distributed in normal tissues, as lamellar or squamous epithelium. In malignant epithelial cells, the degradation of the cell that makes a lot of CK19 fragment released into the blood, the soluble fragments can be recognized by strains of monoclonal antibody ks19.1(epitope

localized on aa. 311-335 (QSQLSMKAALEDTLAETEARFGAQLA) of the α-helical fragment) and BM19.21 ( epitope localized on aa. 346-359 (LADVRADSERQNQE) of the α-helical fragment) so called CYFRA21 - 1. CYFRA21-1 molecular weight of about 30000 Da. CYFRA21-1 content is rich in malignant lung cancer especially in lung squamous cell carcinoma.

Clone: CK006

Host Animal: Mouse.

Isotype: IgG1

Immunogen: Cytokeratin19 of Mr 40 000; from cultured human MCF-7 cells

Format: Purified, Liquid

Purification: >90% pure (SDS-PAGE). Protein A chromatography.

Concentration&Lot: 3.9 mg/ml

Lot: L190301

Buffer: 0.01M PBS, 0.15M NaCl, pH 7.4

Preservative: None

Applications: Each laboratory should determine an optimum working titer for use in its particular application.

Recommended antibody pair for immunoassay:

Capture: L1C00706

Detection: L1C00705

Storage&Shelf life: Store at -20 C for 3 years. Avoid multiple freeze/thaw cycles.

Product Inquiry

Latest News & Blog Insulin Like Growth Factor Binding Protein 3 (IGFBP3)

Technical Guidelines for Clinical Trials of in Vitro Diagnostic Reagents
2022/11/17

1. Scope of application of in vitro diagnostic reagentsClinical trials of in vitro diagnostic reagents refer to systematic research on the clinical performance of in vitro diagnostic reagents in a cor...
New Crown Self-test Antigen Reagent Raw Materials: Preservatives
2022/11/10

With a market of more than one billion people in China, self-test is extensive and convenient. If the simultaneous screening of antigens and nucleic acids is increased in China, the capacity of this m...
Commonly Used Detection Techniques for Colloidal Gold Test
2022/10/13

Colloidal gold is a commonly used labeling technology. It is a new type of immunolabeling technology that uses colloidal gold as a tracer marker and is applied to antigen and antibody. It has its uniq...
What is Cardiac Marker Test and when Should It Be Done?
2022/10/06

What is cardiac markers test? Cardiac markers refer to myocardial markers that can diagnose cardiac injury including myocardial infarction and myocardial minor injury, mainly including cardiac enzymes...