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Human Recombinant ST2 Protein

ST2, also known as IL-1 R4 and T1, is an Interleukin-1 receptor family glycoprotein that contributes to Th2 immune responses (1, 2). Soluble ST2(sST2) is a member of the interleukin 1(IL-1) receptor family existing in blood. And it has been already confirmed to have capacity of capturing IL-33, inhibiting IL-33/ST2 signal transferring, and rise significantly in mechanical overloading cardiac cells. As a result, soluble ST2 can be detected in the blood when heart failure or chronic heart failure exacerbation, or heart muscle can not expand and contract because of cicatrization caused by AMI.     

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Specification Of Human Recombinant ST2 Protein

Source: E.coli 

Purification: Affinity purified. 

Concentration: 1.4mg/ml

Buffer: 10mMpbs, PH=7.4, 1mm EDTA,0.1% SKL,0.2%NaN3 

Preservative: 0.2%NaN3 

Storage & Shelf life: Store at -20C for 3 years. Avoid multiple freeze/thaw cycles.


Application Of Human Recombinant ST2 Protein

Suitable for use as a standard in immunoassay, immunogen for antisera production, and tracer for iodination. Each laboratory should determine an optimum working titer for use in its particular application. 


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