Source: E. Coli
Species: Homo sapiens
Molecular weight: 95KD（with Tag protein)
Purity: >95% by SDS-PAGE
Formulation: The MCM5 solution contains 10mM PBS (pH 7.4), 0.1%SKL, 1mMEDTA.
Application: ELISA; Positive Control; Immunogen; SDS-PAGE; WB. Other applications have not been tested.
Storage & Expiration: Upon receipt, aliquot and store at <-20℃. for long term. Avoid repeated freeze and thaw cycles.
Background: MCM5 Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.