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MCM5 Antigen

Recombinant Minichromosome Maintenance Deficient 5 (MCM5)
CDC46; P1-CDC46; Cell Division Cycle 46; DNA replication licensing factor MCM5


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MCM5 Antigen Specifications


Catalog #: L2C03301

Source: E. Coli

Species: Homo sapiens

Molecular weight: 95KD(with Tag protein)

Concentration: 

Lot #:

Purity: >95% by SDS-PAGE

Formulation: The MCM5 solution contains 10mM PBS (pH 7.4), 0.1%SKL, 1mMEDTA.

Application: ELISA; Positive Control; Immunogen; SDS-PAGE; WB. Other applications have not been tested.

Storage & Expiration: Upon receipt, aliquot and store at <-20℃. for long term. Avoid repeated freeze and thaw cycles.

Background: MCM5 Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES

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