Human Recombinant Soluble ST2 (sST2 / IL1RL1)
- Analyte
- IL-33 receptor · IL1RL1 · soluble ST2
- Source
- Recombinant protein
- Reference
- Q01638
- Documentation
- Lot-specific CoA with every batch · SDS/MSDS and HPLC/MS data on request
- Availability
- Evaluation quantity, standard and bulk — quoted per order
Soluble ST2 (sST2) is a circulating biomarker of cardiac stress and adverse remodelling, providing prognostic information in heart failure independently of BNP and troponin. As the soluble receptor of IL-33 it is also a central reagent for IL-33/ST2 signalling research in immunology and inflammation. Supplied as a high-purity recombinant protein with lot-specific CoA.
| Category | Recombinant protein / IVD biomarker raw material |
|---|---|
| Species / origin | Human recombinant |
| Aliases | IL-33 receptor · IL1RL1 · soluble ST2 |
| Molecular weight | Construct-dependent — stated on the batch CoA |
| Application | Immunoassay development, calibrators & controls, IL-33/ST2 signalling studies |
| Format | Carrier-free and tagged formats available — confirmed per product |
| Purity | Reported per lot on the CoA. Methods used: SDS-PAGE (subunit purity by size) and HPLC / SEC-HPLC (monomer and aggregate distribution) — ask us which method a figure came from |
| Endotoxin | Not a fixed catalogue value. Grades available on request: < 1.0 EU/µg (standard) or < 0.1 EU/µg (cell-based work); the figure for the lot shipped is stated on its CoA |
| Form | Lyophilised (liquid formats on request) |
| Storage | -20 °C to -80 °C |
| Packaging | Evaluation size / 1 mg / custom — bulk quantities on request |
| Documentation | CoA with every batch; MS, HPLC and SDS data on request |
| Price | On request |
Reference sequence & construct notes
| Reference (UniProt) | Q01638 |
|---|---|
| Commonly used construct | IL1RL1 (ST2), isoform 2 — commonly expressed as Lys19–Phe328 |
| Molecular weight | Predicted and apparent molecular weight depend on the construct actually shipped; both are stated on the batch CoA |
| Tag options | Untagged / carrier-free, His, hFc — confirmed per product |
| Purity methods | SDS-PAGE and HPLC / SEC-HPLC, reported per lot |
| Endotoxin grades | < 1.0 EU/µg standard; < 0.1 EU/µg for cell-based work |
| Form & storage | Lyophilised; -20 °C to -80 °C; see the CoA for the lot |
Reference sequence information is given to help you choose a construct, not as a specification of the material shipped. Construct, tag, expression system and lot data are stated on the batch CoA — tell us if your assay is sensitive to any of these and we will confirm before you order.
Ordering options for this item
Three different requests, three different answers — pick the one that matches where you are.
Request an evaluation sample Request a quotation Request documents
One subject line each — send it as it opens and we will have what we need to answer. If you already hold a lot number, add it and we will locate its record.
Questions buyers ask about this item
Can this be supplied in a different format, grade or pack size?
The format, grade and pack size actually available are confirmed per item. If your assay depends on a specific tag, on carrier-free material, or on particular impurity limits, state it in your enquiry and we will confirm what is available before you commit — rather than after. For a buffer or preservative line, tag and expression-system fields do not apply.
What documentation accompanies this product?
A lot-specific Certificate of Analysis with every batch, and a commercial invoice and packing list with every shipment. HPLC / MS data, SDS/MSDS and a certificate of origin are available on request. See the documentation centre.
What are the lead time and minimum quantity?
Lead time and minimum order quantity depend on availability, grade and destination, and are stated on your quotation. Evaluation quantities are available for research groups qualifying a lot against an existing assay.
Can you reserve the same lot for my reorders?
Where stock allows, yes — a consistent lot avoids re-validation work. Ask us at the time of your first order and we will confirm availability rather than promising it later.
For research use and in-vitro diagnostic development only. Not for human or animal therapeutic use. Specifications are stated per lot on the accompanying CoA.
Not sure which grade to specify? Read the specification guide — purity, endotoxin, tag format and expression system all change what the material can be used for.
Request a Quote or Sample
Tell us your application, target purity and quantity — we reply within one business day.