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Applications

Where our materials are used

The same analyte can serve several very different purposes, and the specification that suits one will not suit another. These are the four areas our catalog is built around — if your application is not listed, describe it and we will tell you honestly whether we are the right supplier for it.

Schematic line motif: four abstract application areas joined by a rail. Illustrative diagram.
AntigenSets the reaction.Needs: a defined construct,a stated purity method,and low endotoxin if livingcells are involved.CalibratorAnchors the curve.Needs: carrier-free material,consistent lots, anda matrix that matches yoursample diluent.ControlProves the run.Needs: the same specificationas the calibrator, drawnfrom a characterised lot.Antibody pairReads the signal.Needs: epitope accessibility— a tag sitting whereyour antibody binds breaksthe assay silently.
Four reagent roles, four different specifications. Buying the cheapest material that carries the right analyte name is how assay development loses a month — the requirement changes with the role, not with the label.

Cardiovascular research

Cardiac stress, myocardial injury and coagulation readouts for heart-failure and acute-coronary research, run individually or as a panel.

Inflammation & immunology

Acute-phase and cytokine targets, plus the IL-33/ST2 axis where sST2 functions as a decoy receptor rather than a cardiac readout alone.

IVD assay development

Three distinct roles, three different specifications: antigen for the reaction, calibrator for the curve, control for the run.

Cell-based & signalling studies

Where live cells are involved, endotoxin becomes the deciding specification rather than a footnote — ask for the < 0.1 EU/µg grade. For binding and structural work the deciding variables are conformation and glycosylation rather than endotoxin.

Rather start from the specification?

If you already know the purity, endotoxin and format you need, the comparison page explains what each variable buys you before you talk to anyone.

See the specification guide

Mapping

Matching the material to the application

The same analyte name can hide several different products. The table below maps the applications above to the materials in our catalog and the specification that actually changes with the use.

ApplicationMaterialWhat to specify in your enquiry
sST2 immunoassay developmentHuman recombinant soluble ST2 plus matched mouse monoclonalsRole of each component — capture, detection or calibrator. Capture and labelling antibodies are supplied unconjugated so the pairing chemistry stays yours.
Cardiac injury assays (cTnI)Recombinant cardiac troponin IRecombinant antigen for calibrator and immunogen use; state whether matrix comparability to patient samples matters for your curve.
Thrombosis and fibrinolysis studiesPurified D-dimer antigenAntigen derived from human serum for coating or calibration; goat and rabbit polyclonals are available as pairing partners.
Inflammation readoutsRecombinant CRPPurity grade and endotoxin level if any cell-based work is downstream of the assay.
Assay buffer preparationTRIS buffer and related biological buffersGrade, concentration and pH range; tell us the assay context so preservative-free formats are quoted where conjugation follows.

Representative specifications for the core lines — catalog numbers, lots, concentrations and buffers — are published on the published specifications page, and a side-by-side view is in the specification guide. The lot shipped to you is always described by its own Certificate of Analysis.

Request a Quote or Sample

Tell us your application, target purity and quantity — we reply within one business day.

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